Author

Jakub Stefaniak

University of OxfordORCID 0000-0001-9151-4485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Catherine M. RogersiD· 1 shared Elisabeth M. RothweileriD· 1 shared Esra BalıkçıiD· 1 shared Jennifer WardiD· 1 shared K. HuberiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperSystems Biology

Catherine M. RogersORCID

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1 paper

Recent·Most cited

A chemical biology toolbox to investigate in-cell target engagement and specificity of PRMT5-inhibitors

Elisabeth M. Rothweiler, Jakub Stefaniak, Jennifer Ward, Catherine M. Rogers, Esra Balıkçı, K. Huber

The paper develops chemical biology assays to assess PRMT5 inhibitor target engagement and selectivity, revealing SAM's role in inhibitor binding and confirming the specificity of GSK3326595.

bioRxiv · Jan 20, 2022 · PreprintSystems Biology