Author

Kimberly J. McCabe

Simula Research LaboratoryORCID 0000-0001-9153-8313Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

María Hernández MesaiD· 2 shared Padmini RangamaniiD· 2 shared Frédéric J. HoerndliiD· 1 shared Guadalupe C. GarcíaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

María Hernández MesaORCID

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2 papers

Recent·Most cited

BiophysicsBiophysical JournalPeer-reviewedJan 28, 2025

Synaptic cleft geometry modulates NMDAR opening probability by tuning neurotransmitter residence time

María Hernández Mesa, Kimberly J. McCabe, Padmini Rangamani

This study shows how synaptic geometry affects NMDAR activation by altering neurotransmitter residence time and receptor opening probabilities.

8 citations

statistical modelsynaptic & neural circuits

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 22, 2023

Spine apparatus modulates Ca2+ in spines through spatial localization of sources and sinks

María Hernández Mesa, Guadalupe C. García, Frédéric J. Hoerndli…·Padmini Rangamani

The paper develops a stochastic spatial model to study how SER and SA geometry, along with RyR localization, influence Ca2+ dynamics in dendritic spines and dendrites.

3 citations

statistical model

𝕏 PostBluesky