Author

Guadalupe C. García

Salk Institute for Biological StudiesORCID 0000-0002-2227-2483Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:electronic health records· 2 Organism:mouse· 2 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Terrence J. Sejnowski A BiD· 3 shared Thomas M. BartoliD· 3 shared Kristen M. HarrisiD· 2 shared Lyndsey M. KirkiD· 2 shared Padmini RangamaniiD· 2 shared Adam Husar· 1 shared Alexander SkupiniD· 1 shared Christopher T. LeeiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Terrence J. Sejnowski A BORCID

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4 papers

Recent·Most cited

Presynaptic vesicles supply membrane for axonal bouton enlargement during LTP

Lyndsey M. Kirk, Guadalupe C. García, DC Hanka, K Zatyko, Thomas M. Bartol, Terrence J. Sejnowski A B, Kristen M. Harris

The paper investigates how presynaptic vesicle density changes during LTP and links it to axonal bouton enlargement.

Journal of Neuroscience · Jun 2, 2026Peer-reviewedNeuroscience

The presynaptic vesicle cluster transitions from a compact to loose organization during long-term potentiation

Guadalupe C. García, Thomas M. Bartol, Lyndsey M. Kirk, Priyal Badala, Kristen M. Harris, Terrence J. Sejnowski A B

The paper shows that synaptic vesicle clusters become less dense and more dispersed during long-term potentiation, with increased mobility and a transition from compact to loose organization.

bioRxiv · Nov 1, 2024 · PreprintNeuroscience

Spine apparatus modulates Ca2+ in spines through spatial localization of sources and sinks

María Hernández Mesa, Guadalupe C. García, Frédéric J. Hoerndli, Kimberly J. McCabe, Padmini Rangamani

The paper develops a stochastic spatial model to study how SER and SA geometry, along with RyR localization, influence Ca2+ dynamics in dendritic spines and dendrites.

bioRxiv · Sep 22, 2023 · PreprintNeuroscience

Morphological principles of neuronal mitochondria

Rachel Mendelsohn, Guadalupe C. García, Thomas M. Bartol, Christopher T. Lee, Priya Khandelwal, Emily Liu, Donald J. Spencer, Adam Husar, Eric A. Bushong, Sébastien Phan, Guy A Perkins, Mark H. Ellisman, Alexander Skupin, Terrence J. Sejnowski A B, Padmini Rangamani

The paper analyzes mitochondrial morphology in mouse cerebellum neurons using 3D TEM data to quantify structural features that influence metabolic output.

The Journal of Comparative Neurology · Oct 7, 2021Peer-reviewedNeuroscience