Frédéric J. Hoerndli

This study shows that high expression of FLP recombinase in C. elegans causes synaptic trafficking defects, highlighting potential cytotoxicity of tyrosine recombinases at high doses.

This paper shows that activity-dependent mitochondrial ROS signaling in C. elegans drives avoidance plasticity by enhancing synaptic strength and circuit function.

The paper identifies a new class of Dicer-dependent siRNAs in C. elegans, called 23H-RNAs, produced from diverse genomic features.

The paper shows axonal mitochondria regulate dynamic actin through reactive oxygen species, essential for electrical synapses and gentle touch response in C. elegans.

The paper demonstrates that mitochondrial ROS signaling in C. elegans regulates synaptic recruitment of glutamate receptors by modulating calcium uptake and reactive oxygen species production.

The paper develops a stochastic spatial model to study how SER and SA geometry, along with RyR localization, influence Ca2+ dynamics in dendritic spines and dendrites.

This study shows that PTP-3A regulates AMPAR transport and synaptic retention in C. elegans, essential for long-term associative memory.

This paper introduces a microfluidic device using surface acoustic waves to temporarily immobilize C. elegans for high-resolution imaging and behavior analysis.

This study shows that reactive oxygen species modulate calcium signaling to regulate AMPA receptor transport in C. elegans neurons.