Developmental BiologybioRxivPreprint
Toward Improving Immunotolerance for Stem Cell-Derived Islets
Quan Zhou, Hongfei Li, Dario Gerace…·Douglas A. Melton
The paper demonstrates that transplanting human stem cell-derived islets into the mouse testis induces immune tolerance through suppressive cytokines and regulatory T cells, improving islet survival.
DOI 10.1101/2022.09.15.508091