Author

Charbel Machaalani

University Children's Hospital ZurichORCID 0000-0001-9157-7208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:proteomics· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Ana Guerreiro StückliniD· 2 shared Andrea Joseph De MicheliiD· 2 shared Andreas Postlmayr· 2 shared Cynthia E HawkinsiD· 2 shared Uri Y. TaboriiD· 2 shared Adam C Resnick· 1 shared Astrid Sanchez Bergman· 1 shared Bernard CirauloiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Ana Guerreiro StücklinORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 16, 2026

Single-cell multi-omic analyses resolve the cellular diversity of ALK/ROS1/MET/NTRK-fused gliomas in infants and older children

Andrea Joseph De Micheli, Carlos Alberto Oliveira de Biagi, Costanza Lo Cascio…·Ana Guerreiro Stücklin

The paper uses single-cell and spatial multi-omic analyses to characterize cellular diversity in RTK-fused gliomas across pediatric age groups, identifying distinct cancer cell states and myeloid subgroups.

DOI 10.64898/2026.07.16.738862

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologyCell ReportsPeer-reviewedMar 1, 2026

Functionally distinct ALK and ROS1 fusions detected in infant-type hemispheric gliomas converge on STAT3 and SHP2 activation

Andreas Postlmayr, Astrid Sanchez Bergman, Jacob Torrejon-Diaz…·Ana Guerreiro Stücklin

The paper identifies functionally distinct ALK and ROS1 fusions in infant-type hemispheric gliomas, showing they converge on STAT3 and SHP2 activation through different mechanisms.

2 citationstop 3%

humanproteomics

𝕏 PostBluesky