NeuroscienceLife Science AlliancePeer-reviewed
TBK1 activity regulates the directionality of axonal transport of signalling endosomes
David Villarroel‐Campos, Jose Norberto S. Vargas, Riccardo Zenezini Chiozzi…·Giampietro Schiavo
The paper shows TBK1 phosphorylates Rab7 to regulate unidirectional retrograde transport of signalling endosomes in motor neurons, linking TBK1 dysfunction to ALS-related transport impairments.
2 citations