David Villarroel‐Campos

This study shows that the Gars{Delta}ETAQ mutation in mice causes specific peripheral nerve pathology in motor and sensory neurons, affecting multiple functions and providing a model for CMT2D research.

This study shows BDNF enhances axonal regeneration in human motor neurons by regulating RNA metabolism and cytoskeletal dynamics through kinase pathways.

The paper shows TBK1 phosphorylates Rab7 to regulate unidirectional retrograde transport of signalling endosomes in motor neurons, linking TBK1 dysfunction to ALS-related transport impairments.

This study identifies sex-dependent motor neuron dysfunction and cargo-specific axonal transport impairments in FUS-ALS mice, linking endosomal transport defects to denervation in ALS.

The paper investigates how aging affects signaling endosome transport in motor axons and finds that processivity is impaired, which is not rescued by BDNF treatment due to reduced TrkB receptor expression.