Author
National Hospital for Neurology and NeurosurgeryORCID 0009-0007-6899-8240Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jose Norberto S. Vargas, Anna‐Leigh Brown, Kai Sun…·Giampietro Schiavo
This study shows BDNF enhances axonal regeneration in human motor neurons by regulating RNA metabolism and cytoskeletal dynamics through kinase pathways.
David Villarroel‐Campos, Jose Norberto S. Vargas, Riccardo Zenezini Chiozzi…·Giampietro Schiavo
The paper shows TBK1 phosphorylates Rab7 to regulate unidirectional retrograde transport of signalling endosomes in motor neurons, linking TBK1 dysfunction to ALS-related transport impairments.
Sam Bryce-Smith, Anna‐Leigh Brown, Puja R. Mehta…·Pietro Fratta
The paper identifies novel cryptic polyadenylation events induced by TDP-43 loss in ALS/FTD using bioinformatic methods and shows their potential disease relevance and impact on protein translation.