Author

Dirk DB Bier

Forschungszentrum JülichORCID 0000-0001-9231-4303Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandro GiorgettiiD· 1 shared Bernd NeumaieriD· 1 shared Giulia RossettiiD· 1 shared Jonas GoßeniD· 1 shared Paolo CarloniiD· 1 shared Rui Pedro RibeiroiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Alejandro GiorgettiORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintMar 31, 2023

AI-based novel-chemotype GPCRs drugs: introducing ligand type classifiers and systems biology

Jonas Goßen, Rui Pedro Ribeiro, Dirk DB Bier…·Giulia Rossetti

The paper presents an AI-based method to identify novel chemotype ligands for GPCRs by combining structural data, a random forest classifier, and a kinetic model, demonstrating its effectiveness with a new antagonist for the adenosine A2A receptor.

2 citations

humanproteomics

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