Bernd Neumaier

This study evaluates the safety, dosimetry, and pharmacokinetics of 7-[18F]Fluorotryptophan as a PET tracer for visualizing serotonin synthesis in the brain.

This study shows that autophagy regulator ATG5 protects cerebellar Purkinje cells by maintaining glycolytic activity, preventing neurodegeneration through regulation of glucose transporter 2.

The paper investigates spatial disorientation and hemispheric neurodegeneration in TgF344-AD rats, finding asymmetrical neurodegeneration and impaired spatial memory.

This study identifies a genetic variant in ADORA2A associated with alpha power in EEG and A1 adenosine receptor availability in the human brain, with sex-specific effects observed.

This study shows that caffeine intake during chronic sleep restriction reduces grey matter volume, with effects modulated by A1 adenosine receptor availability.

This study shows that mice with severe loss of nigral dopamine neurons due to mtDNA mutations still maintain motor function through preserved striatal innervation.

The paper presents an AI-based method to identify novel chemotype ligands for GPCRs by combining structural data, a random forest classifier, and a kinetic model, demonstrating its effectiveness with a new antagonist for the adenosine A2A receptor.

This study examines the relationship between EEG microstates, resting-state fMRI networks, and neurotransmitter receptor availability using simultaneous PET-MR-EEG data, finding a stronger association with GABAA receptor binding than mGluR5 or glucose metabolism.

This study identifies a common molecular mechanism involving mGluR2 dysfunction linking cognitive deficits and alcohol craving, and develops a biomarker for targeted interventions.