Author

Boris M. Brenerman

Johns Hopkins UniversityORCID 0000-0001-9252-8184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

James TayloriD· 2 shared Katarzyna A. HusseyiD· 2 shared Kiara C. EldrediD· 2 shared Robert J. JohnstoniD· 2 shared Sarah E. HadyniakiD· 2 shared Alexis J. BattleiD· 1 shared Benjamin D. ShapiroiD· 1 shared Derek S. WelsbieiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

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10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

James TaylorORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 13, 2021

Random Forest Factorization Reveals Latent Structure in Single Cell RNA Sequencing Data

Boris M. Brenerman, Benjamin D. Shapiro, Michael C. Schatz, Alexis J. Battle

This study uses random forest regression to uncover latent gene regulatory structures in mouse brain scRNA-seq data, revealing age-related cellular phenotypes not detected by other methods.

DOI 10.1101/2021.09.13.460168

mousescRNA-seq

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Developmental BiologybioRxivPreprintMar 30, 2021

Spatiotemporal specification of human green and red cones

Sarah E. Hadyniak, Kiara C. Eldred, Boris M. Brenerman…·Robert J. Johnston

The paper investigates the spatiotemporal development of M and L cones in the human retina, finding that retinoic acid signaling promotes M cone fate early in development.

2 citations

humanbulk RNA-seq

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Developmental BiologySciencePeer-reviewedOct 11, 2018

Thyroid hormone signaling specifies cone subtypes in human retinal organoids

Kiara C. Eldred, Sarah E. Hadyniak, Katarzyna A. Hussey…·Robert J. Johnston

The paper shows thyroid hormone signaling controls the temporal switch between S and L/M cone fates in human retinal organoids.

285 citationstop 1%

humanexperimental assay

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