Author

Laetitia S. Gaspar

Centro de Neurociências e Biologia CelularORCID 0000-0001-9262-845XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Luís Pereira de AlmeidaiD· 3 shared Magda M. SantanaiD· 3 shared Diana Duarte LoboiD· 2 shared Patrick SilvaiD· 2 shared Rui Jorge NobreiD· 2 shared Sónia DuarteiD· 2 shared Ana Carolina da SilvaiD· 1 shared Ana Rita ÁlvaroiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersNeuroscience

Luís Pereira de AlmeidaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceBrainPeer-reviewedMay 27, 2025

Circadian Rhythms are Disrupted in Patients and Preclinical Models of Machado-Joseph Disease

Rodrigo F.N. Ribeiro, Dina Pereira, Sara Lopes…·Cláudia Cavadas

This study investigates circadian rhythm disruptions in Machado-Joseph disease patients and preclinical models, finding impaired clock gene expression and disrupted activity and temperature rhythms.

5 citations

mousestatistical model

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NeurosciencebioRxivPreprintJan 4, 2024

Small non-coding RNA content in plasma-derived extracellular vesicles distinguish ataxic SCA3 mutation carriers from pre-ataxic and control subjects

Magda M. Santana, Patrick Silva, Maria M Pinto…·Luís Pereira de Almeida

DOI 10.1101/2024.01.04.574044

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintMay 30, 2023

Isolation of Biologically Active Extracellular Vesicles-Associated AAVs for Gene Delivery to the Brain by Size Exclusion Chromatography

Carina Henriques, Miguel Monteiro Lopes, Patrícia Maia Correia de Albuquerque…·Rui Jorge Nobre

This paper optimizes size exclusion chromatography (SEC) for isolating biologically active EV-AAVs for non-invasive brain gene delivery, showing higher recovery and transgene expression efficiency compared to differential ultracentrifugation.

1 citation

mouseexperimental assay

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