Author

Judith A. Kassis

National Institutes of HealthORCID 0000-0001-9268-3213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Anne L. CalofiD· 1 shared Apratim MitraiD· 1 shared Arthur D. LanderiD· 1 shared Christopher J. TracyiD· 1 shared Claudia M. GebertiD· 1 shared Connor M. KeaniD· 1 shared Fountane W ChaniD· 1 shared J. Lesley BrowniD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperGenetics

Anne L. CalofORCID

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3 papers

Recent·Most cited

Polycomb protein binding and looping mediated by Polycomb Response Elements in the ON transcriptional state

J. Lesley Brown, Liangliang Zhang, Pedro P. Rocha, Judith A. Kassis, Ming-an Sun

The paper investigates how Polycomb Response Elements (PREs) function in the ON transcriptional state, showing that PREs can still loop and interact with enhancers while some PcG proteins remain bound.

Science Advances · Apr 24, 2024Peer-reviewedGenetics

The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation

Yuzhong Cheng, Fountane W Chan, Judith A. Kassis

The paper shows that enhancers of the Drosophila engrailed gene are epigenetically regulated by chromatin and autoregulation, with En protein repressing its own expression.

PLoS Genetics · Nov 15, 2023Peer-reviewedDevelopmental Biology

Decreasing Wapl dosage partially corrects transcriptome phenotypes in Nipbl-/+ embryonic mouse brain

Connor M. Kean, Christopher J. Tracy, Apratim Mitra, Matthew T. Van Winkle, Claudia M. Gebert, Jacob A. Noeker, Anne L. Calof, Arthur D. Lander, Judith A. Kassis, Karl E. Pfeifer

This study shows that reducing Wapl dosage partially corrects transcriptome and growth defects in Nipbl-/+ embryonic mouse brains, suggesting cohesin dynamics regulate gene expression.

bioRxiv · May 31, 2022 · PreprintGenetics