Author

Jacob A. Noeker

National Institutes of HealthORCID 0000-0002-4344-3114Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Apratim MitraiD· 2 shared Claudia M. GebertiD· 2 shared Connor M. KeaniD· 2 shared Karl E. PfeiferiD· 2 shared Anne L. CalofiD· 1 shared Arthur D. LanderiD· 1 shared Beenish RahatiD· 1 shared Beth A. KozeliD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Apratim MitraORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintMay 31, 2022

Decreasing Wapl dosage partially corrects transcriptome phenotypes in Nipbl-/+ embryonic mouse brain

Connor M. Kean, Christopher J. Tracy, Apratim Mitra…·Karl E. Pfeifer

This study shows that reducing Wapl dosage partially corrects transcriptome and growth defects in Nipbl-/+ embryonic mouse brains, suggesting cohesin dynamics regulate gene expression.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyeLifePeer-reviewedAug 17, 2021

Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA

Ki-Sun Park, Beenish Rahat, Hyung Chul Lee…·Karl E. Pfeifer

The paper shows that maternal loss of imprinting at the H19/IGF2 locus causes cardiac pathologies in mice, with Igf2 driving transient hypertrophy and H19 causing progressive fibrosis and reduced ventricular function.

14 citations

mouseexperimental assay

𝕏 PostBluesky