Author

Ai Takahashi-Nakazato

Okinawa Institute of Science and Technology Graduate UniversityORCID 0000-0001-9271-5844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:spatial domain detection· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

D. MercieriD· 2 shared Hiroto AshitomiiD· 2 shared Kazumasa Z. TanakaiD· 2 shared Ming-Ching ChiangiD· 2 shared Yu-Ju LiniD· 2 shared Anton MaximoviD· 1 shared Arisa HiranoiD· 1 shared K Tsutsumi· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

D. MercierORCID

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2 papers

Recent·Most cited

Artificial hibernation uncovers distinct interaction dynamics in functional and pathological state change

D. Mercier, Ming-Ching Chiang, Viviane M. Saito, Yu-Ju Lin, Hiroto Ashitomi, Minami Oshiro, Ai Takahashi-Nakazato, Kazumasa Z. Tanaka

This study uses artificial hibernation to show that neural network reorganization can occur without functional impairment and may prevent pathological state progression.

bioRxiv · Oct 24, 2026 · PreprintNeuroscience

Artificial hibernation uncovers distinct synaptic engram architecture for memory retention

Yu-Ju Lin, Ai Takahashi-Nakazato, K Tsutsumi, Taiga Takahashi, D Mercier, Hiroto Ashitomi, Ming-Ching Chiang, Matthias Georg Haberl, Marco Uytiepo, Anton Maximov, Y Makino, Tomomi Nemoto, Ryosuke Enoki, Arisa Hirano, Kohei Soga, , Kazumasa Z. Tanaka

This study uses a mouse model of artificial hibernation to show that specific synaptic engram structures are preserved despite widespread spine and synapse elimination, suggesting their role in long-term memory retention.

bioRxiv · Dec 11, 2025 · PreprintNeuroscience