Lijing Wang

This study shows that sleep-dependent reactivation of engram neurons in the hippocampal dentate gyrus is subregion-specific and linked to changes in biosynthetic processes during memory consolidation.

The paper investigates how sleep loss affects ribosome-associated transcripts in specific brain regions and cell types, finding region- and cell type-specific changes in transcripts related to synaptic plasticity and cellular timekeeping.

The paper shows that sleep-associated reactivation of visual engram neurons in mice is necessary for fear memory consolidation.

The paper shows sleep loss disrupts hippocampal memory consolidation by activating somatostatin interneurons and cholinergic inputs, which inhibit memory-related activity.

The paper examines how learning and sleep affect ribosomal mRNA profiles in hippocampal neurons, finding that sleep loss disrupts post-learning transcript changes more in active neurons.