Sha Jiang

Sleep-dependent engram reactivation during hippocampal memory consolidation is associated with subregion-specific biosynthetic changes

This study shows that sleep-dependent reactivation of engram neurons in the hippocampal dentate gyrus is subregion-specific and linked to changes in biosynthetic processes during memory consolidation.

Hypnotic treatment reverses NREM sleep disruption and EEG desynchronization in a mouse model of Fragile X syndrome to rescue memory consolidation deficits.

Binocular visual experience and sleep promote visual cortex plasticity and restore binocular vision in a mouse model of amblyopia

This study shows that binocular visual experience and sleep together restore visual cortex function in a mouse model of amblyopia.

Sleep loss drives brain region- and cell type-specific alterations in ribosome-associated transcripts involved in synaptic plasticity and cellular timekeeping

The paper investigates how sleep loss affects ribosome-associated transcripts in specific brain regions and cell types, finding region- and cell type-specific changes in transcripts related to synaptic plasticity and cellular timekeeping.

Binocular vs. monocular recovery experience differentially promote recovery from visual deficits in a mouse model of amblyopia

This study compares binocular and monocular recovery experiences in a mouse amblyopia model, finding binocular recovery more effective for visual function restoration.

Causal role for sleep-dependent reactivation of learning-activated sensory ensembles for fear memory consolidation

The paper shows that sleep-associated reactivation of visual engram neurons in mice is necessary for fear memory consolidation.

Sleep loss disrupts hippocampal memory consolidation via an acetylcholine- and somatostatin interneuron-mediated inhibitory gate

The paper shows sleep loss disrupts hippocampal memory consolidation by activating somatostatin interneurons and cholinergic inputs, which inhibit memory-related activity.

Learning and Sleep Have Divergent Effects on Cytosolic and Membrane-Associated Ribosomal mRNA Profiles in Hippocampal Neurons

The paper examines how learning and sleep affect ribosomal mRNA profiles in hippocampal neurons, finding that sleep loss disrupts post-learning transcript changes more in active neurons.