Author

Femke Roig Kuhn

University of MichiganORCID 0000-0002-7518-6343Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Lijing WangiD· 2 shared Sara J. AtoniD· 2 shared Sha JiangiD· 2 shared Alxandr Kane York· 1 shared Amy Ensing· 1 shared August B. SMITiD· 1 shared Brittany C. ClawsoniD· 1 shared Emily J. Pickup· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Lijing WangORCID

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3 papers

Recent·Most cited

NeuroscienceCellsPeer-reviewedApr 21, 2026

A Tiered Approach to Human Synapse Proteomics: Optimized LC-MS/MS Analysis of Whole-Tissue and Synaptosome Preparations from Frozen Post-Mortem Brain Samples

Femke Roig Kuhn, Remco V. Klaassen, Frank Koopmans…·Sabine Spijker

The paper compares whole-tissue and synaptosome proteomics using LC-MS/MS to evaluate synaptic protein detection, recommending a tiered approach for studying brain disorders.

DOI 10.3390/cells15080736

humanproteomics

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NeuroscienceNature CommunicationsPeer-reviewedFeb 22, 2021

Causal role for sleep-dependent reactivation of learning-activated sensory ensembles for fear memory consolidation

Brittany C. Clawson, Emily J. Pickup, Amy Ensing…·Sara J. Aton

The paper shows that sleep-associated reactivation of visual engram neurons in mice is necessary for fear memory consolidation.

73 citationstop 2%

mouseexperimental assay

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NeurosciencebioRxivPreprintAug 2, 2020

Sleep loss disrupts hippocampal memory consolidation via an acetylcholine- and somatostatin interneuron-mediated inhibitory gate

James E. Delorme, Femke Roig Kuhn, Lijing Wang…·Sara J. Aton

The paper shows sleep loss disrupts hippocampal memory consolidation by activating somatostatin interneurons and cholinergic inputs, which inhibit memory-related activity.

DOI 10.1101/2020.08.02.233080

mouseproteomics

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