Victoria Hsiao

The paper introduces bioscrape, a Python package for fast and flexible simulation and parameter estimation of chemical reaction networks in synthetic biology.

The paper designs a pulsatile communication circuit in bacteria to enable dynamic patterning and long-distance communication through model-driven optimization of promoter and RBS strengths.

The paper develops a Bayesian method to infer chemical signal timing and amplitude from population-level response distributions in a temporal logic gate system in E. coli.

The paper investigates integrase dynamics in a cell-free system, finding that sequestration by binding sites dominates dynamics and reporter activation delay correlates with integrase concentration.