Molecular BiologyCellular and Molecular Life SciencesPeer-reviewed
Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers
Anna Stroynowska-Czerwińska, Magdalena Klimczak, Michal Pástor…·Matthias Bochtler
The paper shows that PHD domains in KMT2/MLL proteins bind to H3K4me3 and acetylated promoters/enhancers, with CXXC domains influencing promoter preference and mutations affecting function.
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