Author

Marie‐José Goumans

Leiden University Medical CenterORCID 0000-0001-9344-6746Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexandre DeberiD· 2 shared Francesc VenturaiD· 2 shared Gonzalo Sánchez‐DuffhuesiD· 2 shared Marius WitsiD· 2 shared Aida Llucià ValldeperasiD· 1 shared Anke M. SmitsiD· 1 shared Arie O. VerkerkiD· 1 shared Arthur A.M. WildeiD· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Alexandre DeberORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedJun 17, 2025

PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

José Antonio Valer, Alexandre Deber, Marius Wits…·Francesc Ventura

This study confirms that PI3K inhibition with BYL719 prevents heterotopic ossification by blocking osteochondroprogenitor specification and reducing inflammation.

DOI 10.7554/elife.91779

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 21, 2025

Multi-omics reveals global signaling rewiring and identifies Activin A-induced dysregulation of FOS/Activator Protein 1 as a novel target in Fibrodysplasia ossificans progressiva

Marius Wits, Nerea Gomez-Suarez, Alexandre Deber…·Gonzalo Sánchez‐Duffhues

The paper uses multi-omics analyses to identify signaling dysregulation in FOP, highlighting AP-1 as a novel therapeutic target.

DOI 10.1101/2025.01.21.634061

humanproteomics

𝕏 PostBluesky

GeneticsbioRxivPreprintJan 16, 2025

The Brugada syndrome associated gene WT1 impacts on SCN5A expression and cardiac conduction

E. Madelief Marsman, Joost Allard Offerhaus, Thomas Stervinou…·Fernanda M. Bosada

This study shows WT1 regulates SCN5A expression and cardiac conduction in Brugada syndrome through a regulatory element in the RV.

DOI 10.1101/2025.01.16.633330

mousehuman

𝕏 PostBluesky

Developmental BiologyDevelopmentPeer-reviewedSep 6, 2021

Prrx1b directs pro-regenerative fibroblasts during zebrafish heart regeneration

Dennis E. M. de Bakker, Mara Bouwman, Esther Dronkers…·Jeroen Bakkers

This study identifies Prrx1b's role in directing pro-regenerative fibroblasts during zebrafish heart regeneration, reducing fibrosis and promoting tissue repair.

43 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky