BiochemistrybioRxivPreprint
Ultra-high throughput in vitro translation assay for identification of Trypanosoma cruzi-specific protein synthesis inhibitors
Camila Colombari Mantovani, Carolina Borsoi Moraes, Guilherme Rodrigo Reis Monteiro dos Santos…·Sérgio Schenkman
This paper develops an ultra-high throughput in vitro translation assay for identifying T. cruzi-specific protein synthesis inhibitors and identifies quinazoline compounds that inhibit translation in both the assay and live parasites.
DOI 10.1101/2025.02.02.636133