Loss of MECP2 leads to induction of p53 and cell senescence
Minori Ohashi, Elena Korsakova, Denise E. Allen…·William E. Lowry
This study shows that loss of MECP2 in neurons leads to p53 induction and cell senescence, causing dendritic defects.
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University of California, Los AngelesORCID 0000-0001-9355-9564Unclaimed ORCID profile · follow to get notified of new preprints
63 papers
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Minori Ohashi, Elena Korsakova, Denise E. Allen…·William E. Lowry
This study shows that loss of MECP2 in neurons leads to p53 induction and cell senescence, causing dendritic defects.
Luz D. Orozco, Colin P. Farrell, Christopher J. Hale…·Matteo A. Pellegrini
The paper identifies DNA methylation associations with metabolic syndrome traits in adipose tissue and develops a biomarker for type II diabetes risk.
Kai Fu, Constantinos Chronis, Abdenour Soufi…·Matteo A. Pellegrini
This study compares OSKM reprogramming factor binding in human and mouse fibroblasts, finding conserved mechanisms and species-specific differences in target sites and regulatory networks.