Author

Tuulia Malén

University of TurkuORCID 0000-0001-9357-6364Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 8 Approach:statistical model· 7 Research Focus:differential expression· 6 Assay:imaging· 5 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Lauri NummenmaaiD· 8 shared Severi SantavirtaiD· 5 shared Jarmo A. HietalaiD· 4 shared Pirjo NuutilaiD· 4 shared Valtteri KaasineniD· 4 shared Janne IsojärviiD· 3 shared Jouni TuiskuiD· 3 shared Lihua SuniD· 3 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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8 shared papersNeuroscience

Lauri NummenmaaORCID

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Striatal dopamine synthesis capacity in Parkinson's disease: Effects of age, sex, and body mass index in a large fluorodopa PET cohort

Tuulia Malén, Jouni Tuisku, Marco Bucci, Severi Santavirta, Valtteri Kaasinen, Sakari Kaasalainen, Janne Isojärvi, Jarmo A. Hietala, Juha Rinne, Lauri Nummenmaa

This study investigates how age, sex, and BMI affect striatal dopamine synthesis capacity in Parkinson's disease patients and healthy controls using PET data.

NeuroImage Clinical · Jan 1, 2026Peer-reviewedNeuroscience

A taxonomy for human social perception: Data-driven modelling with cinematic stimuli

Severi Santavirta, Tuulia Malén, Asli Erdemli, Lauri Nummenmaa

The paper identifies eight dimensions of social perception using data from movie clips and participant ratings, showing consistent patterns across different stimuli and populations.

Journal of Personality and Social Psychology · Oct 7, 2024Peer-reviewedNeuroscience

Seasonal variation in D2/3 dopamine receptor availability in the human brain

Lihua Sun, Tuulia Malén, Jouni Tuisku, Valtteri Kaasinen, Jarmo A. Hietala, Juha O. Rinne, Pirjo Nuutila, Lauri Nummenmaa

The paper investigates seasonal variation in D2/3 dopamine receptor availability in the human brain using PET scans and finds a negative correlation between daylength and receptor availability in the striatum.

European Journal of Nuclear Medicine and Molecular Imaging · May 10, 2024Peer-reviewedNeuroscience

Alterations in type 2 dopamine receptors across neuropsychiatric conditions: A large-scale PET cohort

Tuulia Malén, Severi Santavirta, Sven De Mæyer, Jouni Tuisku, Valtteri Kaasinen, Tuomas Kankare, Janne Isojärvi, Juha K. A. Rinne, Jarmo A. Hietala, Pirjo Nuutila, Lauri Nummenmaa

This study examines D2R availability in neuropsychiatric conditions using PET data from 437 individuals, finding reduced availability in Parkinson's disease and altered interregional connectivity in schizophrenia, depression, and violent behavior.

NeuroImage Clinical · Jan 1, 2024Peer-reviewedNeuroscience

Decoding brain basis of laughter and crying in natural scenes.

Lauri Nummenmaa, Tuulia Malén, Sanaz Nazari‐Farsani, Kerttu Seppälä, Lihua Sun, Severi Santavirta, Henry K. Karlsson, Matthew Hudson, Jussi Hirvonen, Mikko E. Sams, Sophie Kerttu Scott, Vesa Putkinen

The paper investigates the neural basis of laughter and crying using fMRI and MVPA, finding distinct brain networks for each emotion with overlapping suppression.

NeuroImage · Apr 6, 2023Peer-reviewedNeuroscience

Brain glucose metabolism and ageing: A 5-year longitudinal study in a large PET cohort

Kyoungjune Pak, Tuulia Malén, Severi Santavirta, Seunghyeon Shin, Hyun-Yeol Nam, Sven De Mæyer, Lauri Nummenmaa

This study tracks brain glucose metabolism over 5 years in middle-aged men, finding regional declines and associations with metabolic, glucose, and heart rate factors.

bioRxiv · Sep 15, 2022 · PreprintNeuroscience

Age and sex dependent variability of type 2 dopamine receptors in the human brain: A large-scale PET cohort

Tuulia Malén, Tomi Karjalainen, Janne Isojärvi, Aki Vehtari, Paul‐Christian Bürkner, Vesa Putkinen, Valtteri Kaasinen, Jarmo A. Hietala, Pirjo Nuutila, Juha O. Rinne, Lauri Nummenmaa

This study examines age and sex differences in striatal D2R availability using a large PET cohort, finding age-related decline and sex differences in D2R levels.

NeuroImage · Mar 31, 2022Peer-reviewedNeuroscience

μ-opioid receptor availability is associated with sex drive in human males

Lauri Nummenmaa, Patrick Jern, Tuulia Malén, Tatu Kantonen, Laura Pekkarinen, Lasse Lukkarinen, Lihua Sun, Pirjo Nuutila, Vesa Putkinen

This study finds that higher mu-opioid receptor availability in specific brain regions is associated with increased sex drive in healthy human males.

Cognitive Affective & Behavioral Neuroscience · Nov 22, 2021Peer-reviewedNeuroscience