Pirjo Nuutila

The paper investigates diurnal and seasonal variations in brain mu-opioid and dopamine D2 receptor signaling in humans using PET data and finds MOR availability increases in the afternoon, with seasonal and trait-anxiety influences.

The paper introduces an automated pipeline for LAFOV PET data analysis, showing reliable parameter estimates and reduced manual effort.

This study shows that day length affects glucose metabolism in the human brain, specifically in the cuneus, over a 5-year period in healthy males.

This study uses fMRI to show that vicarious feeding activates motor and affective brain regions and that these responses decrease with higher BMI.

This study uses PET tracers to noninvasively monitor stem cell-derived islet graft volume and composition in mice, showing strong correlation with actual graft size and beta cell proportion.

The paper investigates seasonal variation in D2/3 dopamine receptor availability in the human brain using PET scans and finds a negative correlation between daylength and receptor availability in the striatum.

This study examines D2R availability in neuropsychiatric conditions using PET data from 437 individuals, finding reduced availability in Parkinson's disease and altered interregional connectivity in schizophrenia, depression, and violent behavior.

This study investigates how secretin induces satiation by modulating brain glucose metabolism and neural activity through the BAT-brain axis in humans.

This study investigates how photoperiod affects mu-opioid receptor availability in brown adipose tissue using PET imaging and immunofluorescence in rats.

This study examines age and sex differences in striatal D2R availability using a large PET cohort, finding age-related decline and sex differences in D2R levels.

The paper investigates the association between CNR1 gene expression and CB1 receptor protein expression in the human brain using PET scans and mRNA data, finding moderate to strong correlations.

This study finds that higher mu-opioid receptor availability in specific brain regions is associated with increased sex drive in healthy human males.

This study investigates the role of cerebral μ-opioid and CB1-receptor systems in human feeding behavior using PET scans and the Dutch Eating Behavior Questionnaire.

This study shows that bariatric surgery restores disrupted opioid-dopamine interaction in the ventral striatum of obese individuals.

This study finds seasonal variation in brain mu-opioid receptor availability in humans, showing an inverted U-shaped relationship with daylength.

This study quantifies interindividual variability and hemispheric lateralization of μ-opioid receptors in the human brain using PET and Bayesian modeling.