Alexander Ngo

This study identifies distinct subcortical-cortical circuit disruptions in autism and ADHD using functional connectivity and dynamic causal modeling in a multi-site cohort.

This paper develops a framework to distinguish radial and tangential fiber components in human superficial white matter and examines their microstructural and functional properties.

This study examines how connector hubs in temporal lobe epilepsy patients reorganize compared to healthy controls, finding widespread hub reductions and new hub emergence in contralateral regions.

HippoGenes creates transcriptomic maps of the human hippocampus using spatial statistical models and the Allen Human Brain Atlas, enabling subregional gene expression analysis and disease-related molecular decoding.

This paper introduces a surface-intrinsic framework for hippocampal unfolding that improves alignment accuracy and morphology preservation compared to volumetric methods.

This study examines thalamo-cortical and thalamo-hippocampal functional connectivity in temporal lobe epilepsy, finding reduced connectivity in TLE patients and its association with seizure generalization and surgical outcomes.

This study examines sex differences in structural brain alterations in common epilepsies using neuroimaging data from a large international cohort, finding some regional differences but no significant sex-by-diagnosis interactions.

The paper identifies a reproducible functional connectivity signature in temporal lobe epilepsy through a large-scale connectome-wide analysis.

This study identifies hierarchical neural signatures of language by linking semantic and phonological processing to brain networks using fMRI, myelin measures, and AI models.

MICAFlow provides a fast and robust MRI preprocessing pipeline that translates research workflows into clinical practice, achieving high registration accuracy and data reliability across diverse datasets.

This study shows that human cortical dynamics are influenced by both local geometry and network topology, with transmodal regions showing additional dependence on microstructural and connectivity factors.

This study uses activity flow mapping to show reduced task activation prediction accuracy in TLE and FLE patients, linking intrinsic network dysconnectivity to memory impairments.

This study identifies patient-specific functional biomarkers in temporal lobe epilepsy using multimodal MRI data to predict clinical outcomes and guide precision therapeutics.

This study examines intersubject correlations during naturalistic movie watching and finds they align with functional gradients across different brain networks and spatial scales.

The paper examines how cognitive states like resting and movie watching affect large-scale brain functional connectivity using fMRI data from the HCP and PNI datasets.

The paper examines associations between epilepsy-related polygenic risk scores and brain morphology in children, finding PRS-related cortical thinning linked to structural patterns in TLE-HS patients.

This paper maps global cortical organization by integrating microstructural, connectivity, and functional data with cytoarchitectural maps, revealing a sensory-fugal gradient and functional diversity across brain areas.

The paper identifies structural and functional alterations in cortical regions associated with epileptic spikes and their connected networks using multimodal MRI and EEG.

This study finds reduced cortex-wide connectivity distance in ASD, indicating shorter average connection length and increased short-range connectivity, particularly in transmodal brain systems.

This study investigates cerebral perfusion changes in temporal lobe epilepsy using multimodal imaging and finds widespread CBF reductions linked to structural and network disruptions.

This study shows that pharmaco-resistant temporal lobe epilepsy causes a progressive shift in cortical excitation-inhibition balance, linked to cognitive impairments and seizure frequency.

This study identifies atypical functional topography and reduced hierarchical signal flow in temporal lobe epilepsy, linked to microstructural white matter changes and cognitive impairments.

This study examines age-related changes in grey and white matter in TLE patients across the adult lifespan, finding accelerated aging effects after age 55.

HippoMaps provides a toolbox and data warehouse for mapping and analyzing hippocampal data across multiple modalities and scales.

This study identifies reduced microstructural differentiation in TLE patients, linking it to cognitive dysfunction and network reorganization.

This paper develops a new imaging system to study spinal cord activity in behaving mice, revealing lamina-specific calcium responses in astrocytes and pain-related activity in Tac1 neurons.

This study develops a wearable macroscope to image spinal cord activity in behaving mice and finds that painful stimuli trigger coordinated astrocyte excitation across multiple spinal segments.