Author

Melanie D. Schaffler

Columbia UniversityORCID 0000-0001-9368-5608Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Ishmail Abdus-SabooriD· 2 shared Alice Luo Clayton· 1 shared Benjamin Wen Qing HingiD· 1 shared Brigitta B. GunderseniD· 1 shared Ian Hultman· 1 shared Isabella SucciiD· 1 shared Jacqueline N. CrawleyiD· 1 shared Julie N. Blendy· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Ishmail Abdus-SaboorORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 1, 2023

Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11.2 Deletion Syndrome

Brigitta B. Gundersen, William T. O’Brien, Melanie D. Schaffler…·Yann Hérault

Experiments across four laboratories found that arbaclofen rescued cognitive deficits in mouse models of 16p11.2 deletion, without sedation or significant off-target behavioral effects.

6 citations

mousemachine learning (classical)

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 23, 2022

A critical role for touch neurons in a skin-brain pathway for stress resilience

Melanie D. Schaffler, Micah Johnson, Benjamin Wen Qing Hing…·Ishmail Abdus-Saboor

This study identifies a skin-brain touch pathway involving Mrgprb4-lineage touch neurons that promotes stress resilience by modulating neural activity and corticosterone levels in mice.

2 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 22, 2021

Identification of touch neurons underlying dopaminergic pleasurable touch and sexual receptivity

Leah J. Elias, Melanie D. Schaffler, Isabella Succi…·Ishmail Abdus-Saboor

The paper identifies Mrgprb4-lineage neurons as critical for sexual receptivity and dopaminergic reward from social touch in mice.

10 citations

mouseexperimental assay

𝕏 PostBluesky