Ishmail Abdus-Saboor

The paper shows that somatosensory neuron repertoires in mammals diversify through changes to conserved neuron types, enabling adaptation to different habitats and body forms.

This study identifies spinal oxytocin circuits as a conserved mechanism through which affiliative touch reduces pain and enhances well-being in mice and humans.

The paper introduces an automated device for delivering mechanical stimuli to mice, enabling remote testing and integration with brain recordings to study pain mechanisms.

This study shows that dopamine release dynamics in the nucleus accumbens correlate with blood oxygenation responses during associative learning, revealing a link between dopamine signaling and brain-wide plasticity.

The paper identifies ZBTB7A as a key regulator of MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in the orbitofrontal cortex.

This study identifies the role of the gracile nucleus in mediating tactile sensitivity and mechanical allodynia during neuropathic pain in mice.

Opposing glutamatergic MPN Isolation and mostly GABAergic MPN Reunion neurons in the mouse preoptic hypothalamus encode social need and satiety, with touch as a likely cue.

This study shows that face touch is a key social behavior in naked mole-rats linked to social recognition, with molecular and behavioral evidence supporting its importance.

The paper shows that opposing epigenetic forces in olfactory progenitors spatially restrict stochastic OR choice through transcription and silencing influenced by NFIA, B, and X gradients.

This study identifies a skin-brain touch pathway involving Mrgprb4-lineage touch neurons that promotes stress resilience by modulating neural activity and corticosterone levels in mice.

The paper identifies Mrgprb4-lineage neurons as critical for sexual receptivity and dopaminergic reward from social touch in mice.

The paper maps behavioral signatures of inflammatory pain and its relief in mice using computational tools and identifies that a common anti-inflammatory drug does not fully restore pre-injury behavior.

This study shows that chronic paternal morphine exposure increases offspring sensitivity to morphine's antinociceptive effects in a rat model.

This paper introduces PAWS, a machine-vision tool for automated pain measurement in mice, showing it can distinguish painful from non-painful stimuli and quantify pain severity.

This study assesses evoked and spontaneous pain following tooth pulp injury in mice using behavioral and molecular techniques to uncover pain mechanisms.

This study uses high-speed videography and machine learning to objectively assess mouse pain state through paw withdrawal reflex parameters.

The paper uses genetic tracing in mice to show that nociceptors in different body regions have distinct central arbor structures, which may explain the high spatial acuity for pain in the limbs.