Fabrizio Loiacono

This study shows that reduced intrinsic excitability in cerebellar climbing fibers leads to structural changes and altered synaptic function, suggesting a role in memory encoding and disease pathophysiology.

The paper introduces Rubik, a fluorescent reporter that tracks Cre and Flp recombination sequences and enables optogenetic control through temporal recombination events.

This study shows that tunneling nanotubes (TNTs) enable mitochondrial transfer between BBB cells, rescuing astrocytes from ischemia/reperfusion-induced apoptosis and highlighting pericytes' role in BBB preservation.