Synthetic BiologyNature BiotechnologyPeer-reviewed
Efficient Genetic Code Expansion Without Host Genome Modifications
Alan Costello, Alexander A. Peterson, David L. Lanster…·Ahmed H. Badran
This paper develops a plasmid-based codon compression strategy to improve non-canonical amino acid incorporation in E. coli, enabling the creation of new-to-nature peptides with multiple ncAAs.
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