Ahmed H. Badran

This study structurally characterizes evolved ribosomes with enhanced translation kinetics, revealing how RNA structural adaptations influence translation efficiency.

This paper develops a plasmid-based codon compression strategy to improve non-canonical amino acid incorporation in E. coli, enabling the creation of new-to-nature peptides with multiple ncAAs.

The paper develops hyperactive integrases through directed evolution to efficiently insert large transgenes into specific genomic sites.

This paper develops a genetically encoded system to quantify and evolve RuBisCO-catalyzed CO2 fixation in bacteria, showing agreement with in vitro kinetics and enabling enzyme evolution.