Author

Sandra Seredinski

Goethe University FrankfurtORCID 0000-0001-9385-8708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Marcel H. SchulziD· 3 shared Matthias S. LeisegangiD· 3 shared Ralf Peter BrandesiD· 3 shared Timothy WarwickiD· 3 shared Frederike Boos· 2 shared Ilka WittigiD· 2 shared James A. OoiD· 2 shared Judit Izquierdo Ponce· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Marcel H. SchulzORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 17, 2024

Detection of statistically robust interactions from diverse RNA-DNA ligation data

Simonida Zehr, Sandra Seredinski, Emma Catharina Walsh…·Timothy Warwick

The paper introduces RADIAnT, a computational pipeline for detecting RNA-DNA interactions from ligation data, showing improved accuracy in identifying Malat1-DNA interactions and dynamic chromatin-associated RNAs.

DOI 10.1101/2024.09.17.610461

ChIP-seqstatistical model

𝕏 PostBluesky

Molecular BiologyBasic Research in CardiologyPeer-reviewedJan 26, 2023

The endothelial-specific LINC00607 mediates endothelial angiogenic function

Frederike Boos, James A. Oo, Timothy Warwick…·Matthias S. Leisegang

This study identifies LINC00607 as an endothelial-specific lncRNA that supports angiogenic function by interacting with BRG1 to regulate chromatin accessibility and ERG target gene transcription.

33 citationstop 4%

humannon-human primate

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedNov 2, 2022

HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex

Matthias S. Leisegang, Jasleen Kaur Bains, Sandra Seredinski…·Ralf Peter Brandes

The paper identifies HIF1α-AS1 as a DNA:DNA:RNA triplex-forming lncRNA that interacts with the HUSH complex to repress gene expression and modulates angiogenesis in pulmonary hypertension.

48 citationstop 3%

humanDNA methylation

𝕏 PostBluesky