Author

James A. Oo

Goethe University FrankfurtORCID 0000-0002-2934-7580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Ilka WittigiD· 3 shared Marcel H. SchulziD· 3 shared Matthias S. LeisegangiD· 3 shared Ralf Peter BrandesiD· 3 shared Stefan GüntheriD· 3 shared Timothy WarwickiD· 3 shared Can CaoiD· 2 shared Frederike Boos· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Ilka WittigORCID

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Author profile →

3 papers

Recent·Most cited

Long non-coding RNAs direct the SWI/SNF complex to cell-specific enhancers

James A. Oo, Timothy Warwick, Katalin Pálfi, Frederike Lam, François McNicoll, Cristian Prieto‐Garcia, Stefan Günther, Can Cao, Yinuo Zhou, Alexey A. Gavrilov, Sergey V. Razin, Alfredo Cabrera‐Orefice, Ilka Wittig, Soni Savai Pullamsetti, Leo Kurian, , Matthias S. Leisegang

This study identifies long non-coding RNAs (lncRNAs) as guides for the SWI/SNF complex to cell-specific enhancers, revealing a mechanism for chromatin accessibility and gene expression control.

Nature Communications · Jan 2, 2025Peer-reviewedMolecular Biology

The endothelial-specific LINC00607 mediates endothelial angiogenic function

Frederike Boos, James A. Oo, Timothy Warwick, Stefan Günther, Judit Izquierdo Ponce, Melina Lopez, Diba Rafii, Giulia Buchmann, Duc Minh Pham, Zahraa S. Msheik, Tianfu Li, Sandra Seredinski, Shaza Haydar, Sepide Kashefiolasl, Karl Heinz Plate, , Matthias S. Leisegang

This study identifies LINC00607 as an endothelial-specific lncRNA that supports angiogenic function by interacting with BRG1 to regulate chromatin accessibility and ERG target gene transcription.

Basic Research in Cardiology · Jan 26, 2023Peer-reviewedMolecular Biology

HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex

Matthias S. Leisegang, Jasleen Kaur Bains, Sandra Seredinski, James A. Oo, Nina M. Krause, Chao‐Chung Kuo, Stefan Günther, Nevcin Sentürk Cetin, Timothy Warwick, Can Cao, Frederike Boos, Judit Izquierdo Ponce, Shaza Haydar, Rebecca Bednarz, Chanil Valasarajan, , Ralf Peter Brandes

The paper identifies HIF1α-AS1 as a DNA:DNA:RNA triplex-forming lncRNA that interacts with the HUSH complex to repress gene expression and modulates angiogenesis in pulmonary hypertension.

Nature Communications · Nov 2, 2022Peer-reviewedMolecular Biology