Author

Joseph A. Aspinwall

National Institutes of HealthORCID 0000-0001-9407-8615Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Taís B. SaitoiD· 2 shared Abdulsalam AdegokeiD· 1 shared Adam X. MirandaiD· 1 shared Bárbara WeckiD· 1 shared Clayton O. Jarrett· 1 shared Colton McNinchiD· 1 shared Daniel E. SonenshineiD· 1 shared Forrest H. HoytiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Taís B. SaitoORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 20, 2026

Insights into tick-pathogen interactions - a single cell RNA sequencing approach of transcriptional changes during ehrlichial infection

Abdulsalam Adegoke, Joseph A. Aspinwall, Colton McNinch…·Taís B. Saito

This study uses single-cell RNA sequencing to analyze transcriptional changes in ISE6 tick cells during Ehrlichia muris eauclairensis infection, revealing distinct cell states and time-dependent gene expression patterns.

DOI 10.64898/2026.03.19.712879

scRNA-seqstatistical model

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MicrobiologymBioPeer-reviewedMay 27, 2025

Behavioral Manipulation of Ixodes scapularis by Ehrlichia muris eauclairensis: Implications for Tick-Borne Disease Transmission

Joseph A. Aspinwall, Bárbara Weck, Larissa Almeida Martins…·Taís B. Saito

This study shows Ehrlichia muris eauclairensis alters behavior in Ixodes scapularis nymphs, increasing movement speed, bite site-seeking, and feeding duration, with implications for tick-borne disease transmission.

1 citation

mouseproteomics

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