Adam X. Miranda

This study shows that breast cancer cells induce B cell loss in bone marrow, promoting bone metastasis, and that G-CSF mediates this effect, suggesting B cells and G-CSF as therapeutic targets.

This study identifies a STING-STAT3-SOX18 axis driving EndMT and epigenetic reprogramming in SAVI lung fibrosis, suggesting STING as a therapeutic target.

This study uses single-cell RNA sequencing to analyze transcriptional changes in ISE6 tick cells during Ehrlichia muris eauclairensis infection, revealing distinct cell states and time-dependent gene expression patterns.

The paper identifies islet-specific DNA hypomethylated regions linked to T2D risk by integrating DNA methylation data with GWAS and EHR data.

The paper identifies mutation-specific targets for PIK3CA hotspot mutations using a multi-modal genomics approach and isogenic cell lines.