Pia Abel zur Wiesch

This paper uses mathematical models to determine optimal antibiotic dosing strategies based on the shape of the dose-response curve and bacterial pharmacodynamics.

This paper introduces a mechanistic model to optimize antibiotic combinations by incorporating drug mechanisms and testing synergy in Escherichia coli.

The paper introduces vCOMBAT, a web-based tool for creating and visualizing computational models of bacterial antibiotic target-binding using clinical drug concentration data.