Andrew J. Bryant

This study identifies TREM2 as a regulator of myeloid cell function and immune dysregulation in pulmonary hypertension, showing its role in disease progression and potential as a therapeutic target.

This paper introduces a Bayesian framework for detecting circadian rhythmicity biomarkers across the genome, showing improved false discovery rate control and performance in RNA-sequencing data.

This study identifies age-dependent and tissue-specific changes in the circadian transcriptome of male mice, showing reduced rhythmic gene expression and increased variability in aged tissues.

This paper introduces likelihood-based methods to detect circadian rhythmicity and differential circadian patterns in transcriptomic data, showing improved error control and power in simulations and real data.