Haocheng Ding

This study shows that tyrosine hydroxylase-mediated neuroimmune signaling in glioblastoma affects antitumor immunity and enhances oncolytic virotherapy efficacy.

This study shows that BTK inhibition enhances oncolytic virotherapy in glioblastoma by promoting tertiary lymphoid structure formation and improving immune cell infiltration.

This paper introduces a Bayesian framework for detecting circadian rhythmicity biomarkers across the genome, showing improved false discovery rate control and performance in RNA-sequencing data.

This study shows that cardiomyocyte Bmal1 is essential for sex-specific gene expression in the adult mouse heart, as its loss reduces sex differences in circadian transcriptomes.

CosinorTest is an R Shiny app for circadian and differential analysis of transcriptomic data using Cosinor models, offering tools for rhythmicity detection, differential pattern assessment, and visualization.

This study evaluates AB-free kava's effects on tobacco smoke-exposed mice, showing it mitigates health deficits with safety, suggesting potential for reducing tobacco-related harm.

The paper develops linear mixed model methods to detect circadian rhythmicity and differential circadian patterns using repeated measurements, showing improved statistical power and validity.

This paper introduces likelihood-based methods to detect circadian rhythmicity and differential circadian patterns in transcriptomic data, showing improved error control and power in simulations and real data.