Astrocytes instructively regulate neuronal translation
Wendy Liu, Carson C. Schultz, Eshaan A Khan…·Eric Klann
This study shows astrocytes regulate neuronal translation through secreted proteins, with implications for neurodegenerative diseases.
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New York UniversityORCID 0000-0001-9440-6519Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Wendy Liu, Carson C. Schultz, Eshaan A Khan…·Eric Klann
This study shows astrocytes regulate neuronal translation through secreted proteins, with implications for neurodegenerative diseases.
Harrison Tudor Evans, Srinidhi Venkatesan Kalavai, Victor Wu…·Eric Klann
This study shows that tau mutations slow ribosomal elongation, causing collisions that activate the integrated stress response, impairing memory and contributing to neurodegeneration.
Ashley L. Lennox, Mariah L. Hoye, Ruiji Jiang…·Elliott H. Sherr
This study identifies DDX3X mutations as causing neurodevelopmental disorders by disrupting RNA metabolism and neurogenesis during fetal cortical development.