Astrocytes instructively regulate neuronal translation
Wendy Liu, Carson C. Schultz, Eshaan A Khan…·Eric Klann
This study shows astrocytes regulate neuronal translation through secreted proteins, with implications for neurodegenerative diseases.
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Boston UniversityORCID 0000-0003-1888-0520Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Wendy Liu, Carson C. Schultz, Eshaan A Khan…·Eric Klann
This study shows astrocytes regulate neuronal translation through secreted proteins, with implications for neurodegenerative diseases.
Jean-Christophe Delpech, Srinidhi Venkatesan Kalavai, Dhruba Pathak…·Tsuneya Ikezu
This study shows that tau propagation from entorhinal cortex to hippocampal CA1 neurons leads to sex-specific cognitive and electrophysiological impairments, driven by distinct neuroimmune responses in males and females.
Harrison Tudor Evans, Srinidhi Venkatesan Kalavai, Victor Wu…·Eric Klann
This study shows that tau mutations slow ribosomal elongation, causing collisions that activate the integrated stress response, impairing memory and contributing to neurodegeneration.
Jean-Christophe Delpech, Hana Yeh, Srinidhi Venkatesan Kalavai…·Seiko Ikezu
This study shows that inhibiting CSF1R in male MIA offspring improves sociability and memory, while female offspring show no improvement, highlighting sex-specific therapeutic potential.
Harrison Tudor Evans, Drew I. Adler, María Clara Sellés…·Eric Klann
This study maps the spatiotemporal dynamics of de novo protein synthesis in mice brains after auditory threat conditioning using a novel labelling technique.
Zhi Ruan, Dhruba Pathak, Srinidhi Venkatesan Kalavai…·Tsuneya Ikezu
This study investigates how Alzheimer's disease-derived extracellular vesicles propagate tau pathology and affect GABAergic neuronal transmission.