Author

Steve Caplan

Fred and Pamela Buffett Cancer CenterORCID 0000-0001-9445-4297Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Devin FrisbyiD· 2 shared Naava NaslavskyiD· 2 shared Ajay B. Murakonda· 1 shared Bazella Ashraf· 1 shared Kanika DhawaniD· 1 shared Leonardo Almeida-SouzaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Devin FrisbyORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 11, 2026

Branched actin constrains endosomal cargo to control sorting and fission

Devin Frisby, Naava Naslavsky, Steve Caplan

This study shows branched actin, specifically via ARP2/3, is essential for endosomal cargo sorting, fission, and recycling, with inhibition leading to cargo accumulation and subdomain disruption.

DOI 10.64898/2026.03.10.710749

humanexperimental assay

𝕏 PostBluesky

Cell BiologyMolecular Biology of the CellPeer-reviewedOct 9, 2024

Endosomal actin branching, fission and receptor recycling require FCHSD2 recruitment by MICAL-L1

Devin Frisby, Ajay B. Murakonda, Bazella Ashraf…·Steve Caplan

This study identifies MICAL-L1's role in recruiting FCHSD2 to endosomes, which is essential for actin branching, fission, and receptor recycling.

12 citations

humanexperimental assay

𝕏 PostBluesky