A pooled image-based CRISPR screen identifies EAF1 as a T. gondii modulator of ESCRT subversion.
Einar Birnir Olafsson, Christophe-Sébastien Arnold, Jacob A. Kellermeier, Patrick A. Rimple, Hargobinder Kaur, Yifan Wang, Jonathan Z. Sexton, Staffan G. Svärd, Vern B. Carruthers, Matthew J. O’Meara
The paper identifies EAF1 as a Toxoplasma gondii effector that modulates ESCRT subversion using a pooled image-based CRISPR screening framework called spaCR.
bioRxiv · Jul 9, 2026 · PreprintMicrobiology