Xian Zhang

This study shows that oral Nicotinamide Riboside (NR) treatment protects retinal ganglion cells (RGCs) and optic nerve axons in DBA/2J mice, likely through increased retinal NAD+ levels, and also prevents iris depigmentation and delayed IOP elevation.

This study shows that systemic NR treatment protects against retinal degeneration in three mouse models by preserving retinal function and structure and increasing NAD+ levels.

This study investigates the protective effects of HIOC and TUDCA on retinal ganglion cell (RGC) death following optic nerve crush in mice, finding significant RGC survival in treated groups.