Elisa Pedone

This study designs new pluripotency maintenance protocols by leveraging cellular response dynamics to reduce drug exposure while maintaining pluripotency in mouse embryonic stem cells.

Cheetah is a computational toolkit that integrates real-time microscopy analysis with cellular control algorithms, demonstrating improved segmentation accuracy over thresholding methods in bacterial and mammalian cells.

ChipSeg segments bacterial and mammalian cells in microfluidic devices using thresholding, enabling fluorescence quantification and cell tracking in time-lapse experiments.

The paper develops a dual-input system to dynamically regulate gene expression and protein stability in mouse embryonic stem cells, enabling precise control of protein levels and faster response times.

This study demonstrates automated control of pluripotency in mouse embryonic stem cells using microfluidics and feedback algorithms to regulate Rex1 expression.