Author

Francesco Aulicino

University of BristolORCID 0000-0002-3097-3765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Maria Pia CosmaiD· 2 shared Adrian JaniszewskiiD· 1 shared An ZwijseniD· 1 shared Anchel De Jaime-SogueroiD· 1 shared Annekatrien BoeliD· 1 shared Annick Francis· 1 shared Antonio Lo NigroiD· 1 shared Bernard K. van der VeeriD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Maria Pia CosmaORCID

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3 papers

Recent·Most cited

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency

Paraskevi Athanasouli, Martina Balli, Anchel De Jaime-Soguero, Annekatrien Boel, Sofia Papanikolaou, Bernard K. van der Veer, Adrian Janiszewski, Tijs Vanhessche, Annick Francis, Youssef El Laithy, Antonio Lo Nigro, Francesco Aulicino, Kian Peng Koh, Vincent Pasque, Maria Pia Cosma, , Frederic Lluı́s

This study shows that Wnt/TCF7L1 repression promotes primitive endoderm differentiation in mESCs by inhibiting naive and formative pluripotency factors.

Nature Communications · Mar 3, 2023Peer-reviewedDevelopmental Biology

Baculovirus-vectored precision delivery of large DNA cargoes in human genomes

Francesco Aulicino, Martin Pelosse, Christine Toelzer, Julien Capin, Erwin Ilegems, Parisa Meysami, Ruth Rollarson, Per‐Olof Berggren, Mark Simon Dillingham, Christiane Schaffitzel, Moin Ahson Saleem, Gavin Iain Welsh, Imre Berger

This paper develops a baculovirus-based system for delivering large DNA cargoes for CRISPR-based genome editing in human cells, achieving up to 30% correct interventions.

Nucleic Acids Research · Jul 8, 2022Peer-reviewedSynthetic Biology

A tunable dual-input system for ‘on-demand’ dynamic gene expression regulation

Elisa Pedone, Lorena Postiglione, Francesco Aulicino, Dan L. Rocca, Sandra Montes-Olivas, Mahmoud Khazim, Diego di Bernardo, Maria Pia Cosma, Lucia Marucci

The paper develops a dual-input system to dynamically regulate gene expression and protein stability in mouse embryonic stem cells, enabling precise control of protein levels and faster response times.

Nature Communications · Oct 2, 2019Peer-reviewedSynthetic Biology