Vairavan Lakshmanan

This study shows that PABP2 is essential for neoblast differentiation during planarian regeneration, as its deficiency disrupts progenitor formation and tissue organization.

ctQC improves biological inferences by applying cell-type-specific quality control to single cell and spatial transcriptomics data, enhancing clustering and reducing artifacts.

The paper identifies MCV oncoproteins' regulation of miR183 cluster and piR62011 in MCC, and screens for therapeutic molecules targeting miR182.

This study identifies DDX24 as essential for planarian head regeneration by regulating muscle organization, pole specification, and Wnt signaling.

This study identifies and characterizes tRNA-derived fragments (tRFs) in planarians, revealing their role in regeneration and highlighting their interaction with SMEDWI proteins and potential involvement of Dicers.

The paper shows that modulation of β-catenin levels is essential for the transition of cranial neural crest cells from a collective to a dispersed state in the first pharyngeal arch.

This study shows that EHMTs regulate heterochromatin anchoring to the nuclear periphery via LaminB1 methylation and reveals their role in aging-related nuclear changes.

The paper identifies and functionally characterizes tRNA-derived small RNAs (tsRNAs) in cell state transitions, showing their role in regulating translation and stem cell states.