Dasaradhi Palakodeti

This study shows that Angiogenin activity is essential for RNA remodeling during the maternal-to-zygotic transition in mouse embryos, affecting transcript clearance, small-RNA dynamics, and RNA granule organization.

This study shows that oxygen and mechanical cues interact to define distinct cellular states in 3D environments through a reciprocal regulatory coupling.

The paper shows that actin remodeling during wound healing inactivates ERK1/2, unmasking DNMT3a's nuclear localization signal and enabling its nuclear translocation to regulate epigenetic reprogramming.

This study shows that calcium regulates pluripotency, cell cycle, differentiation, and post-translational/post-transcriptional processes in mESCs through pCaMKII-dependent mechanisms.

This study identifies TIP60 as essential for wound response in planarians through its role in stem cell maintenance and regeneration.

The paper identifies ddx43+ cells as regulators of slow-cycling neoblasts in planaria using single-cell transcriptomics and functional analyses.

This study investigates planarian light-sensing strategies, revealing their ability to use both spatial and temporal light information for navigation and orientation.

This study analyzes ribosomes from wild-type and FMR1 knockout human embryonic stem cells, revealing altered translation rates and rRNA methylation patterns linked to FMRP's role in translational regulation.

This study shows that PABP2 is essential for neoblast differentiation during planarian regeneration, as its deficiency disrupts progenitor formation and tissue organization.

This study shows that FMRP regulates the 2O-methylation pattern of rRNA during neuronal differentiation, which affects protein synthesis and is disrupted in Fragile X Syndrome.

This study shows that Drosophila larval macrophages reprogram their metabolism in response to high sugar diets, with mixed effects on growth, where lipogenic shifts promote growth but are insufficient to counteract other metabolic changes.

The paper identifies synapse-enriched lncRNAs in mouse hippocampus and shows their roles in synapse development and fear memory consolidation.

This study identifies the functional roles of FMRP domains in translation regulation, showing that the C-terminus mediates ribosome binding and repression, while domain synergy is needed for granule formation and microtubule association.

The paper identifies ES30L, an expansion segment in ribosomal RNA, as potentially regulating translation by interacting with transcripts and RNA-binding proteins.

This study identifies DDX24 as essential for planarian head regeneration by regulating muscle organization, pole specification, and Wnt signaling.

This study identifies and characterizes tRNA-derived fragments (tRFs) in planarians, revealing their role in regeneration and highlighting their interaction with SMEDWI proteins and potential involvement of Dicers.

The paper sequences 1000 SARS-CoV-2 genomes from India, revealing multiple circulating lineages, predominant A2a haplotype with D614G mutation, and geographic mutation clustering.

The paper shows that modulation of β-catenin levels is essential for the transition of cranial neural crest cells from a collective to a dispersed state in the first pharyngeal arch.

This study shows that EHMTs regulate heterochromatin anchoring to the nuclear periphery via LaminB1 methylation and reveals their role in aging-related nuclear changes.

The paper identifies and functionally characterizes tRNA-derived small RNAs (tsRNAs) in cell state transitions, showing their role in regulating translation and stem cell states.