NeurosciencebioRxivPreprint
A role for Hypoxia Inducible Factor 1a (HIF1a) in intermittent hypoxia-dependent changes to spatial memory and synaptic plasticity
Alejandra Arias‐Cavieres, Maggie A. Khuu, Chinwendu U. Nwakudu…·Alfredo J. Garcia
This study shows that intermittent hypoxia increases HIF1a in wildtype mice, leading to oxidative stress, reduced NMDA receptors, and impaired LTP in the hippocampus, which contributes to memory deficits.
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