Author

Derek Bowie

McGill UniversityORCID 0000-0001-9491-8768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chloe C KoensiD· 2 shared Federico Míguez‐CabelloiD· 2 shared Adriano SenatoreiD· 1 shared Alessandra AleottiiD· 1 shared Anders S. KristenseniD· 1 shared Anhadvir SinghiD· 1 shared Bernard PirotteiD· 1 shared Boris S. ZhoroviD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Chloe C KoensORCID

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2 papers

Recent·Most cited

NeuroscienceCommunications BiologyPeer-reviewedJul 3, 2025

Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan Epsilon receptor

Anhadvir Singh, Boris S. Zhorov, Luis Alfonso Yáñez-Guerra…·Adriano Senatore

The paper investigates the evolution and functional properties of Epsilon receptors in placozoa, revealing molecular determinants for ligand specificity and polyamine regulation.

5 citations

proteomicsstatistical model

𝕏 PostBluesky

NeuroscienceJournal of Structural BiologyPeer-reviewedJul 28, 2024

Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538

Yasmin Bay, Federico Míguez‐Cabello, Chloe C Koens…·J.S. Kastrup

The paper reports the crystal structure of the GluK1 ligand-binding domain complexed with kainate and the full-spanning positive allosteric modulator BPAM538, showing its unique binding mode and selectivity for GluK1.

5 citations

protein structureexperimental assay

𝕏 PostBluesky